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Elsevier, Journal of Biological Chemistry, 12(288), p. 8279-8288, 2013

DOI: 10.1074/jbc.m112.421370

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Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation*

Journal article published in 2013 by Tanja Kosenko, Mia Golder, Geoffrey Leblond, Willy Weng ORCID, Thomas A. Lagace
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background: Secreted PCSK9 regulates LDL levels in plasma by mediating degradation of hepatic LDL receptors.