Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Wýrtz, P.; Kettunen, Johannes; Tukiainen, Taru; Ap, Sarin; Sarin, Antti-Pekka; Ortega-Alonso, Alfredo; Tikkanen, Emmi; Lp, Lyytikäinen; Lyytikäinen, Leo-Pekka; Aj, Kangas; Kangas, Antti J.; Soininen, Pasi; Würtz, Peter; Silander, Kaisa; Dick, Danielle M.; Dm, Dick; Rj, Rose; Rose, Richard J.; Mj, Savolainen; Savolainen, Markku J.; Viikari, Jorma; Kähönen, Mika; Lehtimäki Terho, J.; Lehtimäki, Terho; Pietil Currency Signinen, Kh; Kh, Pietiläinen; Pietiläinen, Kirsi H.; Inouye, Michael; McCarthy, Mark I.; Mi, McCarthy; Jula, Antti; Eriksson, Johan; Ot, Raitakari; Raitakari, Olli T.; Salomaa, Veikko; Kaprio, Jaakko; J. Currency Signrvelin, M.-R.; Järvelin, Marjo-Riitta; Mr, Järvelin; Peltonen, Leena; Perola, Markus; Freimer, Nelson B.; Nb, Freimer; Ala-Korpela, Mika; Palotie, Aarno; Ripatti, Samuli

Tools

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Journal article published in 2012 by P. Wýrtz, Johannes Kettunen, Taru Tukiainen, Sarin Ap, Antti-Pekka Sarin, Alfredo Ortega-Alonso, Emmi Tikkanen, Lyytikäinen Lp, Leo-Pekka Lyytikäinen, Kangas Aj, Antti J. Kangas, Pasi Soininen, Peter Würtz

, Kaisa Silander, Danielle M. Dick and other authors.

This paper is available in a repository.

Full text: Download

Preprint: policy unknown

Upload

Postprint: policy unknown

Upload

Published version: policy unknown

Upload

Abstract

Nuclear magnetic resonance assays allow for measurement of a wide range of metabolic phenotypes. We report here the results of a GWAS on 8,330 Finnish individuals genotyped and imputed at 7.7 million SNPs for a range of 216 serum metabolic phenotypes assessed by NMR of serum samples. We identified significant associations (P

Links

Tools

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Abstract