Most therapies do not discriminate between normal and cancerous cells, leading to toxicity and unwanted side effects. In this sense, the oleuropein, minor component of extra virgin olive oil, is an excellent candidate due to its antitumorals estates described so much in vitro and in vivo experiments in colon, breast and skin cancer, and the capacity to across the blood brain barrier. The recent results obtained in glia tumoral cells line, tumors characterized by its complicated treatment and worse prognosis; make to the oleuropein an exceptional candidate for the treatment of cancer.