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Elsevier, The Lancet, 9197(355), p. 39-40

DOI: 10.1016/s0140-6736(99)05582-8

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Hypocretin (orexin) deficiency in human narcolepsy

Journal article published in 2000 by Seiji Nishino, Beth Ripley, Sebastiaan Overeem, Gert Jan Lammers ORCID, Emmanuel Mignot
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.