Published in
Cell Press, Cancer Cell, 3(1), p. 213-215, 2002
DOI: 10.1016/s1535-6108(02)00049-1
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RUNX: a trilogy of cancer genes
Journal article published in 2002 by
Anders H. Lund,
Maarten van Lohuizen
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Abstract
The RUNX family of transcription factors plays pivotal roles during normal development and in neoplasias. Recent data involve RUNX3 as an important tumor suppressor in gastric cancers and pose interesting questions about how perturbed levels and interspecific competition among RUNX family members may contribute to tumorigenesis.