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Humana Press, Methods in Molecular Biology, p. 275-291, 2012
DOI: 10.1007/978-1-61779-585-5_11
Humana Press, Methods in Molecular Biology, p. 533-553, 2019
DOI: 10.1007/978-1-4939-9074-0_17
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Association Mapping and Disease: Evolutionary Perspectives
Journal article published in 2012 by
Søren Besenbacher 
,
Bjarni J. Vilhjálmsson,
Thomas Mailund,
Mikkel H. Schierup
,
Bjarni J. Vilhjálmsson,
Thomas Mailund,
Mikkel H. Schierup
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Abstract
In this chapter, we give a short introduction to the genetics of complex disease with special emphasis on evolutionary models for disease genes and the effect of different models on the genetic architecture, and finally give a survey of the state-of-the-art of genome-wide association studies.