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Taylor and Francis Group, Expert Review of Vaccines, 11(9), p. 1257-1274, 2010

DOI: 10.1586/erv.10.120

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Carbohydrate-based vaccines: Challenges and opportunities

Journal article published in 2010 by Yen-Lin Huang ORCID, Chung-Yi Wu
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Advances in the synthesis of oligo- or polysaccharides and new technologies developed in glycobiology studies have opened a new avenue in carbohydrate vaccine design. In principle, various types of cell-surface epitopes, characteristic of the invading organism or related to aberrant growth of cells, can be applied to develop vaccines. Numerous promising carbohydrate-based vaccine candidates have been prepared in recent years. This article, primarily for general readers, briefly presents the recent advances involving carbohydrate-based vaccines, including antibacterial, antiparasite, anticancer and antivirus vaccines.