Oxford University Press, The Oncologist, 11(19), p. 1115-1117, 2014
DOI: 10.1634/theoncologist.2014-0304
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Hepatocellular carcinoma (HCC) is a highly complicated disease characterized by comorbid cirrhosis and disease heterogeneity. Given multiple failures in the past, we need to learn from previous experiences and generate novel ideas to increase the chance of success. More effort and patience should be exercised in the selection of a homogeneous patient population and identification of predictive markers during drug development for HCC.