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Elsevier, Cell, 2(113), p. 144-145, 2003

DOI: 10.1016/s0092-8674(03)00277-0

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Muscle or fat? Rho bridges the GAP.

Journal article published in 2003 by Alan R. Saltiel ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Mesenchymal stem cells can differentiate into muscle or fat cells, depending on the exposure to growth factors. The Rho GTPase appears to play a crucial role in this decision of cellular fate, promoting myogenesis and inhibiting adipogenesis.