Published in

Nature Research, Nature Immunology, 9(10), p. 934-936, 2009

DOI: 10.1038/ni0909-934

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The sickness unto Deaf

Journal article published in 2009 by James M. Gardner ORCID, Mark S. Anderson
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

While promiscuous expression of tissue-specific antigens (TSAs) in the thymus is essential for self-tolerance, immunologically relevant TSA expression may also occur in the secondary lymphoid organs. A new study links the transcriptional regulator Deaf1 with altered TSA expression in the secondary lymphoid organs and autoimmune diabetes.