Published in
Elsevier, Journal of Biological Chemistry, 15(288), p. 10406-10417, 2013
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Tetramerization of SAMHD1 Is Required for Biological Activity and Inhibition of HIV Infection*
Journal article published in 2013 by
Junpeng Yan,
Sarabpreet Kaur,
Maria DeLucia,
Caili Hao,
Jennifer Mehrens,
Chuanping Wang,
Marcin Golczak,
Krzysztof Palczewski,
Angela M. Gronenborn 
,
Jinwoo Ahn,
Jacek Skowronski
,
Jinwoo Ahn,
Jacek Skowronski
This paper is made freely available by the publisher.
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Abstract
Background: SAMHD1, a dGTP-activated dNTPase, inhibits retrovirus infection at the reverse transcription step in monocytes and quiescent T lymphocytes.