Published in

Elsevier, Bioorganic and Medicinal Chemistry, 5(17), p. 1997-2001, 2009

DOI: 10.1016/j.bmc.2009.01.027

Links

Tools

Export citation

Search in Google Scholar

Effects of the introduction of inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT

Journal article published in 2009 by Veronica Esposito, Antonella Virgilio, Antonietta Pepe, Giorgia Oliviero, Luciano Mayol ORCID, Aldo Galeone ORCID
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Insight into the influence of inversion of polarity sites on the structural features of quadruplex structures is presented. The NMR and CD studies concern modified oligodeoxynucleotides (ODNs) based on the quadruplex forming sequence TGGGT. The presence of inversion of polarity sites not only does not compromise the formation of quadruplexes, but in some cases it increases the thermal stability of modified complexes compared with that of the unmodified one.