Autoimmune pancreatitis is reported to account for approx-imately 5% of all causes of chronic pancreatitis. herein, we describe a patient with Sjogren's syndrome, who had been diagnosed with pancreatic cancer three years earlier, but had declined any surgical intervention. The presence of Sjogren's syndrome, the benign course over the ascending three years, the elevated serum IgG4 with a subsequent decline after ther-apy and a normalization of pancreatic size following gluco-corticoid therapy are all suggestive of autoimmune pancre-atitis. Recognition of this clinical entity may save patients from unnecessary surgery.