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Nature Research, Nature Cell Biology, 9(14), p. 904-906, 2012

DOI: 10.1038/ncb2569

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Regulating intraflagellar transport

Journal article published in 2012 by Lotte B. Pedersen, Soren T. Christensen ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.