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American Society for Cell Biology, Molecular Biology of the Cell, 10(26), p. 1918-1934

DOI: 10.1091/mbc.e14-11-1530

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SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors

Journal article published in 2015 by Sergio A. Mojica, Kelley M. Hovis, Matthew B. Frieman, Bao Tran, Ru-Ching Hsia, Jacques Ravel ORCID, Clifton Jenkins-Houk, Katherine L. Wilson, Patrik M. Bavoil
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

SINC, a secreted effector of Chlamydia psittaci, uniquely targets the inner nuclear membrane of infected cells and uninfected neighbors. Candidate partners include ELYS, lamin B1, and four proteins of the inner nuclear membrane, suggesting that SINC interacts with host proteins that control nuclear structure, signaling, and chromatin organization.