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Elsevier, Blood Cells, Molecules and Diseases, 4(54), p. 348-352

DOI: 10.1016/j.bcmd.2015.01.008

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Review: Beta-thalassemia and molecular chaperones

Journal article published in 2015 by Afshan Sumera ORCID, Ammu Radhakrishnan ORCID, Abdul Aziz Baba, Elizabeth George
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.