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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 4(51), p. 1512-1514, 2007

DOI: 10.1128/aac.00959-06

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In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.