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Wiley-VCH Verlag, ChemInform, 27(32), p. no-no, 2010

DOI: 10.1002/chin.200127120

Elsevier, Tetrahedron, 8(57), p. 1593-1600

DOI: 10.1016/s0040-4020(00)01120-0

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Intramolecular trapping of amides by 1-lithio-1-bromocyclopropanes

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Reaction of 2-acylaminomethyl-1,1-dibromocyclopropanes with methyllithium at −90°C leads to selective bromine-lithium exchange and cyclisation to give a 1-bromo-3-azabicyclo[3.1.0]hexan-2-ol.