OBJECTIVE: To investigate inflatable bouncer–related injuries to children in the United States. METHODS: Records were analyzed from the National Electronic Injury Surveillance System for patients ≤17 years old treated in US emergency departments (EDs) for inflatable bouncer–related injuries from 1990 to 2010. RESULTS: An estimated 64 657 (95% confidence interval [CI]: 32 420–96 893) children ≤17 years of age with inflatable bouncer–related injuries were treated in US EDs from 1990 to 2010. From 1995 to 2010, there was a statistically significant 15-fold increase in the number and rate of these injuries, with an average annual rate of 5.28 injuries per 100 000 US children (95% CI: 2.62–7.95). The increase was more rapid during recent years, with the annual injury number and rate more than doubling between 2008 and 2010. In 2010, a total of 31 children per day were treated in US EDs for an inflatable bouncer–related injury, which equals a child every 46 minutes nationally. A majority of patients were male (54.6%), and the mean patient age was 7.50 years (95% CI: 7.17–7.83). Most injuries were fractures (27.5%) and strains or sprains (27.3%), and most injuries occurred to the lower (32.9%) or upper (29.7%) extremities. Most injuries occurred at a place of sports or recreation (43.7%) or at home (37.5%), and 3.4% of injured children were hospitalized or kept for <24 hours for observation. CONCLUSIONS: The number and rate of pediatric inflatable bouncer–related injuries have increased rapidly in recent years. This increase, along with similarities to trampoline-related injuries, underscores the need for guidelines for safer bouncer usage and improvements in bouncer design to prevent these injuries among children.