Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 9(51), p. 3364-3366, 2007
DOI: 10.1128/aac.00347-07
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Innate Protection of Mycobacterium smegmatis against the Antimicrobial Activity of Nitric Oxide Is Provided by Mycothiol
Journal article published in 2007 by
Christopher C. Miller,
Mamta Rawat,
Todd Johnson,
Yossef Av-Gay 
This paper is made freely available by the publisher.
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Abstract
ABSTRACT Nitric oxide (NO) is an efficient antimicrobial agent. A role for mycothiol in protecting mycobacteria from nitrosative damage was revealed by showing that a Mycobacterium smegmatis mutant is sensitive to NO. A direct correlation between NO and mycothiol levels confirmed that mycothiol is important for protecting mycobacteria from NO attack.