Dissemin is shutting down on January 1st, 2025

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Elsevier, Psychiatry Research, 2-3(180), p. 151-152

DOI: 10.1016/j.psychres.2009.12.006

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Further evidence supporting the association between 5HTR2C gene and bipolar disorder

Journal article published in 2010 by Marianna Mazza, Laura Mandelli, Giovanni Martinotti, Marco Di Nicola ORCID, Daniela Tavian, Gloria Negri, Elisa Colombo, Sara Missaglia, Diana De Ronchi, Roberto Colombo, Luigi Janiri ORCID, Alessandro Serretti
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Three 5HTR2C polymorphisms were investigated in bipolar (BD) spectrum disorders. The functional rs6318 G (Cys) allele was more frequent in BD patients than in controls (P=0.0036). Thus, 5HTR2C may have a role in BD. Further investigation is required to understand its involvement in co-morbidity for substance use disorders (SUDs).