Published in
Elsevier, Journal of Investigative Dermatology, 2(134), p. 313-314, 2014
DOI: 10.1038/jid.2013.506
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Crossing Barriers; Restoring Barriers? Filaggrin Protein Replacement Takes a Bow
Journal article published in 2014 by
Alan D. Irvine 
This paper is made freely available by the publisher.
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Abstract
In this issue of the Journal, Stout and colleagues report a novel and creative approach to replacement of genetically determined absence or deficiency of epidermal proteins. While these early data are certainly interesting, further validation work is required to determine the utility of this approach in genodermatoses.