There are several aspects that might influence the performance achieved by existing learning systems. It has been reported that one of these aspects is related to class imbalance in which examples in training data belonging to one class heavily outnumber the examples in the other class. In this situation, which is found in real world data describing an infrequent but important event, the learning system may have di#culties to learn the concept related to the minority class. In this work we perform a broad experimental evaluation involving ten methods, three of them proposed by the authors, to deal with the class imbalance problem in thirteen UCI data sets. Our experiments provide evidence that class imbalance does not systematically hinder the performance of learning systems. In fact, the problem seems to be related to learning with too few minority class examples in the presence of other complicating factors, such as class overlapping. Two of our proposed methods, Smote + Tomek and Smote + ENN, deal with these conditions directly, allying a known over-sampling method with data cleaning methods in order to produce better-defined class clusters. Our comparative experiments show that, in general, over-sampling methods provide more accurate results than under-sampling methods considering the area under the ROC curve (AUC). This result seems to contradict results previously published in the literature. Smote + Tomek and Smote + ENN presented very good results for data sets with a small number of positive examples. Moreover, Random over-sampling, a very simple over-sampling method, is very competitive to more complex over-sampling methods. Since the over-sampling methods provided very good performance results, we also measured the syntactic complexity of decision trees induc...