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Oxford University Press (OUP), Bioinformatics, 17(29), p. 2208-2210

DOI: 10.1093/bioinformatics/btt371

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Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Summary: We have developed Cake, a bioinformatics software pipeline that integrates four publicly available somatic variant-calling algorithms to identify single nucleotide variants with higher sensitivity and accuracy than any one algorithm alone. Cake can be run on a high-performance computer cluster or used as a stand-alone application.