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American Association for the Advancement of Science, Science Signaling, 382(8), 2015

DOI: 10.1126/scisignal.2005918

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Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Finding compounds that target a specific phosphatase-substrate interaction may yield immunosuppressive drugs with fewer side effects.