The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study
Journal article published in 2007 by
L. Roccatogliata,
L. Roccatagliata,
Ma Rocca,
P. Valsasina 
,
L. Bonzano,
Mp Sormani,
R. Saccardi,
M. G. Marrosu,
Gl L. Mancardi,
G. La Nasa,
M. Filippi,
E. Cocco,
Cherchi,
Alessandra Lugaresi ,
C. Ialori
and other authors.
,
L. Bonzano,
Mp Sormani,
R. Saccardi,
M. G. Marrosu,
Gl L. Mancardi,
G. La Nasa,
M. Filippi,
E. Cocco,
Cherchi,
Alessandra Lugaresi ,
C. Ialori
and other authors.
This paper is made freely available by the publisher.
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Abstract
Using MRI, we measured disease activity and brain atrophy in nine multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT) for a mean follow up of 63 months. We show that AHSCT is associated to a longlasting suppression of inflammation and to a marked decrease of the rate of brain atrophy after the second year following treatment. Multiple Sclerosis 2007; 13 : 1068—1070. http://msj.sagepub.com