Elsevier, Value in Health, 3(11), p. A63-A64, 2008
DOI: 10.1016/s1098-3015(10)70211-4
Elsevier, Vaccine, 37-38(25), p. 6677-6691
DOI: 10.1016/j.vaccine.2007.07.018
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Using WHO-CHOICE methodology, we calculated cost-utility ratios for various interventions (PAP smear, HPV-DNA testing, VIA and vaccination against HPV) at various frequencies to reduce the burden of cervical cancer and condyloma (in the case of the HPV vaccination) in Israel, which has a low prevalence of cervical cancer. Assuming non-waning efficacy, HPV vaccinations will become cost-effective, very cost-effective and cost saving when the cost per dose falls below $96.85, $50.42 and $27.20, respectively. Attempts should be made to raise compliancy with PAP smears from the current opportunistic 12.2-20.0% per annum either before and/or after the vaccination is introduced.