In Greece the most important tourism activity occurs in coastal and island areas. Mountain areas have remained unexploited despite of their proximity to urban centers, their satisfactory road network and most of all their natural beauty and their beneficial environmental conditions. This study investigates the bioclimatic performance of Nafpaktia, a mountainous area in West Greece, in order to evaluate their ability for tourism development. For this reason, sensors of air temperature and humidity located in selected places of the above area at various altitudes with different aspects. Bioclimatic performance of these selected places was evaluated by "Humidex Index". The results showed that rise of altitude leads to decrease of Humidex values, forming improved bioclimatic conditions. The selected areas are suitable for tourism development. Nevertheless, the most beneficial conditions were recorded at west and east aspects with the highest altitude areas.