Patients who have acute Kawasaki disease (KD) should be treated promptly with intravenous immunoglobulin (IVIG) to prevent coronary artery abnormalities (based on strong research evidence). (19) Patients who have persistent or recrudescent fever following primary therapy with IVIG should receive another dose of IVIG at 2 g/kg (based primarily on consensus). (9) Other secondary therapies to consider include corticosteroids (14)(20) and infliximab (21) (based on some research evidence). Echocardiography is an excellent modality for assessing coronary artery changes in children who have early KD (based primarily on consensus). In patients who have KD and always-normal coronary arteries, preventive cardiology counseling and followup are recommended until further studies delineate the long-term consequences on endothelial health (9) (based on some research evidence as well as consensus). In patients who have KD and coronary aneurysms, cardiologic follow-up is tailored to the degree of coronary artery involvement and involves assessment of coronary function and structure (based on strong research evidence). (9).