Published in

BioMed Central, BMC Infectious Diseases, 1(14), 2014

DOI: 10.1186/1471-2334-14-224

Links

Tools

Export citation

Search in Google Scholar

Diagnostic and prognostic utilities of multimarkers approach using procalcitonin, B-type natriuretic peptide, and neutrophil gelatinase-associated lipocalin in critically ill patients with suspected sepsis

Journal article published in 2014 by Mina Hur, Hanah Kim ORCID, Seungho Lee, Flavia Cristofano, Laura Magrini, Rossella Marino, Chiara Serena Gori, Cristina Bongiovanni, Benedetta Zancla, Patrizia Cardelli, Salvatore Di Somma
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Abstract Background We investigated the diagnostic and prognostic utilities of procalcitonin (PCT), B-type natriuretic peptide (BNP), and neutrophil gelatinase-associated lipocalin (NGAL) in critically ill patients with suspected sepsis, for whom sepsis was diagnosed clinically or based on PCT concentrations. Methods PCT, BNP, and NGAL concentrations were measured in 340 patients and were followed up in 109 patients. All studied biomarkers were analyzed according to the diagnosis, severity, and clinical outcomes of sepsis. Results Clinical sepsis and PCT-based sepsis showed poor agreement (kappa = 0.2475). BNP and NGAL showed significant differences between the two groups of PCT-based sepsis ( P  = 0.0001 and P