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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(52), p. 1790-1793, 2008

DOI: 10.1128/aac.01440-07

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Multiclonal Outbreak of Klebsiella pneumoniae Producing Extended-Spectrum β-Lactamase CTX-M-2 and Novel Variant CTX-M-59 in a Neonatal Intensive Care Unit in Brazil

Journal article published in 2008 by Doroti de Oliveira Garcia, Yohei Doi, Dora Szabo, Jennifer M. Adams-Haduch, Tânia M. I. Vaz, Daniela Leite, Maria Clara Padoveze ORCID, Maristela P. Freire, Fernanda P. Silveira, David L. Paterson
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT An outbreak of cephalosporin-resistant Klebsiella pneumoniae occurred in a neonatal intensive care unit in São Paulo, Brazil. Of the 10 pulsotypes identified during the outbreak and follow-up periods, nine produced CTX-M-2 or its new variant CTX-M-59 and one produced SHV-5. bla CTX-M-2 / 59 genes were located on closely related plasmids that were transferable.