Springer (part of Springer Nature), Breast Cancer Research and Treatment, 3(89), p. 309-312
DOI: 10.1007/s10549-004-2171-5
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Several published epidemiologic studies show increased breast cancer risk for carriers of the Val-allele at codon 655 of the HER2 gene. We conducted additional analyses using data from three studies, including case-control analyses stratified on age and kin-cohort analyses using relatives of cases and controls. The results provide additional evidence that HER2 codon 655 genotype may predispose to early-onset breast cancer.