Published in
Cell Press, Neuron, 2(77), p. 212-213, 2013
DOI: 10.1016/j.neuron.2013.01.009
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Fragile X Syndrome Therapeutics: Translation, Meet Translational Medicine
Journal article published in 2013 by
Jonathan Lipton,
Mustafa Sahin 
This paper is made freely available by the publisher.
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Abstract
Fragile X syndrome, a common cause of intellectual disability and autism, is thought to occur due to abnormal regulation of neuronal protein synthesis. A study by Osterweil et al. (2013), in this issue, demonstrates that the HMG-CoA reductase inhibitor lovastatin can normalize protein synthesis and also reduce audiogenic seizures in Fmr1 knockout mice.