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American Academy of Neurology (AAN), Neurology, 7(65), p. 1126-1128, 2005

DOI: 10.1212/01.wnl.0000178982.53965.70

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Evidence for progressive gray matter loss in patients with relapsing-remitting MS

Journal article published in 2005 by P. Valsasina ORCID, B. Benedetti, M. Rovaris, M. P. Sormani, G. Comi, M. Filippi
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

Little is known about the temporal evolution of gray matter damage occurring early in the course of multiple sclerosis (MS). The authors investigated the evolution of gray matter volume loss in 117 patients with relapsing-remitting MS, scanned monthly for a 9-month period. Time-trend analysis revealed a decrease of gray matter volumes over the study period (p < 0.001). This study shows that gray matter damage in relapsing-remitting MS evolves markedly over a short period of observation.