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Elsevier, Tetrahedron Letters, 51(49), p. 7268-7270

DOI: 10.1016/j.tetlet.2008.10.024

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Synthesis of porphyrin–quinolone conjugates

Journal article published in 2008 by Fernanda da C. Santos, Anna C. Cunha, Maria Cecília B. V. de Souza ORCID, Augusto C. Tomé, Maria G. P. M. S. Neves, Vitor F. Ferreira ORCID, José A. S. Cavaleiro ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

meso-Tetrakis(pentafluorophenyl)porphyrin reacts with propargyl alcohol to afford porphyrins substituted with one, two, three or four prop-2-yn-1-yloxy groups in the 4-position of the meso-aryl groups. These new porphyrin derivatives react with a 6-azidoquinolone under ‘click-chemistry’ conditions to give porphyrin–quinolone conjugates linked by 1,2,3-triazole units.