Mechanism of Action of Cyclic Oligosquaramides on DPPC Phospholipid Monolayers
Journal article published in 2011 by
Juan J. Giner Casares 
,
Janos Keller,
Carmen Rotger ,
Antoni Costa ,
Gerald Brezesinski
,
Janos Keller,
Carmen Rotger ,
Antoni Costa ,
Gerald Brezesinski
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Abstract
New moiety for drug design: The chemical group squaramide shows promising results in medicinal chemistry. The mechanism of action of cyclic oligosquaramides at biological membranes is revealed by a monolayer study. The biological activity is related to the hydrophobicity of the new squaramide-derivative drugs.