The estimation of flood damage is an important component for risk-oriented flood design, risk mapping, financial appraisals and comparative risk analyses. However, research on flood-loss modelling, especially in the commercial sector, has not gained much attention so far. Therefore, extensive data about flood losses were collected for affected companies via telephone surveys after the floods of 2002, 2005 and 2006 in Germany. Potential loss determining factors were analysed. The new Flood Loss Estimation MOdel for the commercial sector (FLEMOcs) was developed on the basis of 642 loss cases. Losses are estimated depending on water depth, sector and company size as well as precaution and contamination. The model can be applied to the micro-scale, i.e. to single production sites as well as to the meso-scale, i.e. land-use units, thus enabling its countrywide application.Citation Kreibich, H., Seifert, I., Merz, B. & Thieken, A. H. (2010) Development of FLEMOcs – a new model for the estimation of flood losses in the commercial sector. Hydrol. Sci. J.55(8), 1302–1314.