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American Society for Microbiology, Journal of Virology, 3(72), p. 2538-2540, 1998

DOI: 10.1128/jvi.72.3.2538-2540.1998

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Effect of nitric oxide on poliovirus infection of two human cell lines

Journal article published in 1998 by López Guerrero Ja, José Antonio López Guerrero ORCID, Luis Carrasco
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT The role of nitric oxide after poliovirus infection of the human HeLa (carcinoma) and U937 (promonocytic) cell lines has been analyzed. Both types of cells produced detectable levels of nitric oxide after poliovirus infection. However, this production was not sufficient to limit viral productivity. On the other hand, pretreatment with the nitric oxide donor glycerine trinitrate lengthened the course of poliovirus infection.