Slope streaks are gravity-driven albedo features observed on martian slopes since the Viking missions. The debated mechanism of formation could involve alternatively dry granular flow or wet mass wasting. A systematic mapping of slope streaks from the High Resolution Stereo Camera is presented in this paper. Two regions known for their slope streaks activity have been studied, the first one is located close to Cerberus lava flow, and the second one is inside the Olympus Mons Aureole. The statistics of slope streaks shapes measured from orthorectified images confirm previous results from Mars Orbiter Camera surveys. Preferential orientations of slope streaks are reported. Slope streaks occur preferentially on west facing slopes at latitudes lower than 30° N for Olympus and on south–west facing slopes for Cerberus. Wind directions derived from a General Circulation Model during the dusty season correlate with these orientations. Furthermore, west facing slopes at Olympus have a thicker dust cover. These observations indicate that slope streaks are dust avalanches controlled by the preferential accumulation of dust in the downstream side of the wind flow. The paucity of slope streaks at high latitudes and their preferential orientation on south-facing slopes have been presented as an evidence for a potential role of H2O phase transition in triggering or flow. The potential role of H2O cannot be ruled out from our observations but the dust avalanche model together with the atmospheric circulation could potentially explain all observations. The role of H2O might be limited to a stabilizing effect of dust deposits on northward facing slopes at intermediate latitudes (30° N–33° N) and on all slopes further north.