The objective of the study carried out in the Upper Oueme Catchment in Benin (West Africa) was to assess the nutrient status in yam (Dioscorea rotundata) through the Diagnostic and Recommendation Integrated System (DRIS), to compare yield, foliar nutrient concentrations and the variance of nutrients of low-and high-yielding groups. Field experiments were carried out in 2001 and 2002 using a randomized complete block design with four treatments, 2001: n = 80, 2002: n = 109) at three sites: Beterou, Dogue, and Wewe. Nitrogen (N), followed by potassium (K), phosphorus (P), and magnesium (Mg) were identified as the most limiting nutrients in 2001 whereas sulfur (S) followed by N was identified as most limiting ones in 2002. Imbalanced nutrition was observed in both the years but was higher in 2001 compared in 2002. They may be utilized as a basis for calibrating the fertilization program of yam.