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Elsevier, Journal of Allergy and Clinical Immunology, 3(134), p. 604-612, 2014

DOI: 10.1016/j.jaci.2014.07.010

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Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis

Journal article published in 2014 by Yu-Chang B. Wu, Louisa K. James ORCID, Jason A. Vander Heiden, Mohamed Uduman, Stephen R. Durham, Steven H. Kleinstein, David Kipling, Hannah J. Gould ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Fig 3. Patterns of CDR-H3 length. A, Virtual CDR-H3 spectratypes show the relative distribution of clonotypic sequences by CDR-H3 length for unmutated IgM (gray bars) and IgEAR (red bars; AR.IS and AR.OS groups combined). a.a, Amino acids. B, Mean CDR-H3 length was compared between groups, as indicated. C, Nucleotide numbers for different CDR-H3 components in IgE sequences were compared between the IgENA and IgEAR groups (AR.IS and AR.OS groups combined). D, Mean CDR-H3 length for IgE clonotypic sequences was compared between groups in peripheral blood (PB) and nasal biopsy specimens (NB). *P < .05, **P < .005, and ****P < .00005. ns, Not significant.