At the request of the Agency for Nature and Forests (ANB), we investigated the feasibility of grouping 145 European and Flemish priority species into so called multispecies action or recovery plans. As a starting point, we used the classification into landscape and ecological species profiles of Van Uytvanck & Goethals (2014). To add species to the clusters and profiles, we assigned species to biological valuation codes and/or to different types of running waters in Flanders. Additionally, we summarized their distribution into the 12 ecological regions of Flanders. Using one ordination technique (Principal Coordinates Analysis) and two clustering techniques (Ward Hierarchical Clustering and Affinity Propagation Clustering), we added species to or changed species from the existing landscape clusters and ecological profiles. This assignment was subsequently checked by an expert-judgement of the species experts at the INBO and if necessary, species were assigned to more than one cluster of profile. Within the different landscape clusters, we searched for species that were close enough in ecological resource and habitat use to compile multispecies action plans. This way, we reduced the number of species action plans from 145 to 87: 34 multispecies action plans and 53 individual species action plans, a reduction of 40%. When compiling multispecies action plans, we recommend to cross-check synergies and conflicts with other species in the same landscape cluster. To avoid a lack of detail for the different species in a multispecies action plan, we also recommend that all individual species’ ecological resources are mentioned in a multispecies action plan. We also suggest a possible way for prioritisation of species action plans by using the Flemish and/or European Red List status of the different species in each ecological profile. But, since not all species have been assessed against the regional Red List criteria yet, other criteria such as feasibility, expense, social basis, regional responsibility for the European population, etc. should be taken into consideration as well.