Wiley, Cochrane Library, 2020
DOI: 10.1002/14651858.cd001533.pub6
Wiley, Cochrane Library, 2015
DOI: 10.1002/14651858.cd001533.pub5
Wiley, Cochrane Library, 2003
DOI: 10.1002/14651858.cd001533.pub2
Full text: Unavailable
Corticosteroid drugs for several months after a child has nephrotic syndrome can reduce repeat episodes. Nephrotic syndrome is a condition where the kidneys leak protein from the blood into the urine. Most children who experience this syndrome have repeat episodes. When it is untreated, children can often die from infections. Corticosteroid drugs are used to reduce these infections, but the drugs can also have serious side effects. The review of trials found that using corticosteroids for several months after the first episode has an increasing ability to reduce the risk of relapses, without an increase in serious side effects.