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Wiley, Angewandte Chemie International Edition, 28(45), p. 4612-4617, 2006

DOI: 10.1002/anie.200504599

Wiley, Angewandte Chemie, 28(118), p. 4728-4733, 2006

DOI: 10.1002/ange.200504599

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Laser‐Induced Release of Encapsulated Materials inside Living Cells

Journal article published in 2006 by Andre G. Skirtach Dr, Almudena Muñoz Javier, Almudena Muñoz Javier, Oliver Kreft Dr, Oliver Kreft, Karen Köhler, Alicia Piera Alberola, Alicia Piera Alberola, Helmuth Möhwald Prof. Dr, Helmuth Möhwald, Wolfgang J. Parak Dr ORCID, Gleb B. Sukhorukov Prof. Dr
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Abstract

(Figure Presented) Escape route: The laser-initiated release of fluorescently labeled polymers from polyelectrolyte-multilayer microcapsules is demonstrated inside living cancer cells. A polymer is incorporated in capsules with metal nanoparticles in their walls, which serve as light-absorbing centers. The capsules are internalized by cells and near-infrared light ruptures the walls of the capsules, thus releasing the content into the cells.