Elsevier, Journal of Immunological Methods, (410), p. 100-112, 2014
DOI: 10.1016/j.jim.2014.03.022
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Fungi represent emerging infectious threats to human populations worldwide. Mice and other laboratory animals have proved invaluable in modeling clinical syndromes associated with superficial and life-threatening invasive mycoses. This review outlines salient features of common vertebrate animal model systems to study fungal pathogenesis, host antifungal immune responses, and antifungal compounds.