Samples of VC0.85 sandwiched between aluminum disks were compressed in a diamond anvil cell and X-ray diffraction patterns recorded at high pressures up to 53 GPa using synchrotron radiation. The presence of aluminum in the cell rendered the sample pressure nearly hydrostatic and also served as the pressure standard. No phase transformation was observed up to the highest pressure. The measured unit cell volume versus pressure data gave 258 ± 11 GPa and 4.5 ± 0.6 for the bulk modulus and the pressure derivative, respectively.