Ketosis is a metabolic disorder that occurs in cattle when energy demands exceed energy intake and result in a negative energy balance. The current study was designed to evaluate the efficacy of herbal gel AV/KPC/10 (M/S Ayurvet Limited) for control of sub clinical ketosis in cows. 18 animals positive for sub clinical ketosis were randomly divided into Group I (n=6), treated with AV/KPC/10 at dose 200 gm twice a day orally for first two days followed by 100 gm once a day for next 3 days, Group II (n=6), treated with Liquid Anabolite at dose 200ml twice a day orally for two days, followed by 100 ml twice a day for 3 days and Group III (n=6), treated with Inj. Dextrose 25% at dose 500 ml intravenously once in a day for three days. Total 12 healthy cows negative for sub clinical ketosis were selected and divided randomly into two equal groups, control Group IV (n=6), cows negative for sub clinical ketosis were kept without any treatment and treatment Group V (n=6), cows negative for sub clinical ketosis were supplemented with AV/KPC/10. Parameters viz. Ketosis diagnosis, biochemical estimation and milk yield were recorded before treatment ('0' day) and on 3 rd , 7 th and 30 th day post treatment. Statistical analysis of data revealed efficacy of herbal gel AV/KPC/10 (M/S Ayurvet Limited) in control and treatment of Ketosis in cattle.