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European Respiratory Society, European Respiratory Journal, 5(43), p. 1347-1356

DOI: 10.1183/09031936.00058813

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LUNOKID: can numerical American Thoracic Society/European Respiratory Society quality criteria replace visual inspection of spirometry?

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Data provided by SHERPA/RoMEO

Abstract

The gold standard for assessing quality of forced expiratory manoeuvres is visual inspection by an expert. Numeric ATS/ERS quality criteria (NQC) include back extrapolated volume (BEV), repeatability and forced expiratory time (FET). Currently available equipment provides feedback tempting the investigator to use NQC as pass-fail-criteria.To investigate whether using NQC instead of visual acceptability is a valid option, we analysed data from a multi-centre national reference study in Germany of children 4 to 18 years old. Spirometry was performed under field conditions. ROC-analysis was used to assess performance of BEV, repeatability, FET and a combination thereof in relation to visual acceptability.We included data of 3133 healthy Caucasians in the analyses; 72% delivered at least two visually acceptable manoeuvres. Of these 59% would have been rejected based on combined NQC, mainly because the FET criterion was not feasible. Specificity of the NQC was generally low (BEV 10%, repeatability 30%, FET 50%). ROC-analysis showed that a combination of the three measures could reach at best a sensitivity of 90% and specificity of 56%.We conclude that visual control is mandatory, NQC may help obtain the best possible results, but a fixed cut-off for FET should be abandoned.