Published in
American Society for Microbiology, Eukaryotic Cell, 3(7), p. 537-540, 2008
DOI: 10.1128/ec.00448-07
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- American Society for Microbiology | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Toxoplasma gondii and Cryptosporidium parvum Lack Detectable DNA Cytosine Methylation
Journal article published in 2008 by
Mathieu Gissot,
Sang-Woon Choi,
Reid F. Thompson,
John M. Greally 
,
Kami Kim
,
Kami Kim
This paper is made freely available by the publisher.
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Abstract
ABSTRACT Epigenetic factors play a role in the expression of virulence traits in Apicomplexa. Apicomplexan genomes encode putative DNA cytosine methylation enzymes. To assess the presence of cytosine methylation of Toxoplasma gondii and Cryptosporidium parvum DNA, we used mass spectrometry analysis and confirmed that these organisms lack detectable methylcytosine in their DNA.