As the number of Korean adults with diabetes is expected to increase continuously, the health care for these patients is becoming increasingly important. In recent years, the prevention of infectious diseases through vaccination of the adult population has attracted much interest. Patients with diabetes are more vulnerable to various infectious diseases and the prevention of these diseases through adequate vaccination is especially important. With the recent introduction of newly developed vaccines throughout the country, clinicians have more options for vaccinating their patients. In 2012, the Korean Society of Infectious Diseases developed revised guidelines for adult vaccination, which include recommendations for diabetic patients. Generally, vaccines for healthy adults are also recommended for diabetic patients, and these vaccines include those for Streptococcus pneumoniae, influenza, tetanus-diphtheria-pertussis, hepatitis A and B and herpes zoster. In this review, we will focus our discussion on the pneumococcal (PSV-13 and PPSV 23), influenza and zoster vaccines.